Biotin and derivatives
Apexbio Technology LLC NHS-LC-LC-BIOTIN-KIT-2T
NHS-LC-LC-Biotin Kit is used in biochemical and molecular biology research originating from the need to label proteins and other macromolecules with high specificity It operates through NHS ester chemistry allowing biotin to covalently bind to primary amine groups in biological molecules facilitating subsequent detection or purification via biotin-avidin/streptavidin interactions The kit demonstrates robust in vitro activity in nanomolar to low micromolar ranges providing a reliable means for the modification of proteins under controlled conditions Typical applications include cell labeling immunoassays ELISA Western blotting and targeted drug delivery studies It is also employed in cell models and animal studies to track cellular processes or biomolecular interactions Due to its versatility the NHS-LC-LC-Biotin Kit is a staple in drug screening and various experimental setups with concentrations tailored to specific research designs
Medchemexpress LLC CA125 Human Biotin 50ug | 50ug
The CA125 protein acts by binding to MSLN and plays a crucial role in forming a protective and lubricating barrier on mucosal surfaces This interaction promotes heterotypic cell adhesion and is suggested to play an important role in peritoneal metastasis of ovarian cancer CA125 Protein Human (Biotinylated HEK293 His-Avi) is the recombinant human-derived CA125 protein expressed by HEK293 with C-Avi C-His labeled tag
Medchemexpress LLC m-PEG8-NHS ester | 756525-90-3 | MFCD13184969 | 95.0% | 509.54 g/mol | C22H39NO12 | 100 MG
m-PEG8-NHS ester is a methoxy polyethylene glycol (PEG) linker containing an N-hydroxysuccinimide (NHS) ester functional group. It provides an eight-unit PEG spacer for conjugation to primary amines and is used in antibody-drug conjugate (ADC) synthesis and general bioconjugation to increase solubility and reduce aggregation.
- Non-cleavable 8-unit PEG spacer
- Amine-reactive NHS ester for conjugation
- Supplied as a 100 mg vial (research use only)
- Purity by NMR: 95.0%
- Molecular weight 509.54 g/mol; formula C22H39NO12
- Store pure material at -20°C for long-term stability
Medchemexpress LLC DBCO-N-bis(PEG4-NHS ester) | 2639395-38-1 | 96.2% | 995.03 | C49H62N4O18 | 5 MG
DBCO-N-bis(PEG4-NHS ester) is a PEG-based bifunctional linker that contains two PEG4-NHS ester groups and a dibenzocyclooctyne (DBCO) moiety. It is designed for bioconjugation and protein labeling via NHS-ester chemistry and for copper-free click conjugation with azide-containing partners through strain-promoted alkyne-azide cycloaddition (SPAAC).
- Contains two PEG4-NHS ester groups and a DBCO functional group.
- Enables protein modification through NHS-ester conjugation to primary amines.
- Supports copper-free SPAAC click chemistry with azide partners.
- Suitable for small-scale research use; available in 5 mg and larger sizes.
- Molecular weight 995.03; CAS number 2639395-38-1.
Medchemexpress LLC Bis-PEG10-NHS ester | 2221949-02-4 | 95.0% | 752.76 | C32H52N2O18 | 100 MG
Bis-PEG10-NHS ester is a PEG-based linker containing two N-hydroxysuccinimide (NHS) ester groups. It is used as a cleavable linker in the synthesis of antibody-drug conjugates (ADCs) and PROTACs to enable conjugation to primary amines.
- Contains two NHS ester functional groups for amine conjugation.
- Purity typically 95.0%.
- Molecular weight approximately 752.76; formula C32H52N2O18.
- CAS number 2221949-02-4 for unambiguous identification.
- Available in multiple pack sizes, including 100 mg.
- Storage: pure form at -20°C; in solvent store at -80°C for longer-term stability.
Medchemexpress LLC NHS-SS-Ac | 2750799-11-0 | 95.0% | 337.37 | 25 MG
NHS-SS-Ac is an amine-reactive product synthesized from acetic acid. It is intended for research use only.
- Amine-reactive product
- Purity of 95.0%
- Colorless to light yellow oil
- Recommended storage for pure form: -20°C for 3 years or 4°C for 2 years
- Soluble in DMSO (50 mg/mL)
Medchemexpress LLC Biotin-PEG5-NHS ester | 98.0% | 632.72 | 250 MG
Biotin-PEG5-NHS ester is a heterobifunctional crosslinker and a polyethylene glycol-containing bioconjugation reagent. It is utilized in scientific research for developing highly sensitive biosensors, targeted drug delivery systems, immunofluorescence imaging, and protein affinity purification, serving as a tool for precise biomolecule labeling and functionalization.
- Efficiently introduces biotin tags onto primary amine groups.
- Forms stable amide bonds under mild conditions.
- Incorporates a flexible spacer arm for increased molecular freedom.
- Enhances water solubility.
- Reduces non-specific adsorption.
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine conjugated to biotin | 133695-76-8 | MFCD01961045 | 97.5% | 974.36 | C51H96N3O10PS | 50 MG
DSPE-Biotin is a biotinylated phospholipid used as a lipid reagent for biochemical research, liposome formulation, and surface functionalization of nanoparticles. It enables biotin-mediated capture or labeling of lipid assemblies and supports drug-delivery and biochemical assay applications. Store cold and protect from light for best stability.
- Biotinylated phospholipid enabling strong biotin-avidin interactions.
- Suitable for liposome preparation and nanoparticle surface functionalization.
- Facilitates biotin-mediated capture and labeling of lipid assemblies.
- High purity (97.5%) for reproducible experimental results.
- Solid, off-white to light yellow appearance for easy handling.
- Storage: -20°C; in solvent: -80°C (6 months), -20°C (1 month); protect from light.
Medchemexpress LLC Methoxy polyethylene glycol N-hydroxysuccinimide ester | 92451-01-9 | 98.0% | 10MG
Methoxy polyethylene glycol N-hydroxysuccinimide ester, average molecular weight 20,000 Da, is an NHS-activated methoxy-PEG reagent that reacts efficiently with primary amines to form stable amide bonds. It is supplied as a solid for research use and is commonly used for PEGylation of peptides and proteins, linker construction in targeted degraders, and general bioconjugation to improve solubility and pharmacokinetic properties.
- Reacts with primary amines to form stable amide linkages.
- Improves solubility and reduces immunogenicity of conjugates.
- Provides a 20 kDa hydrophilic spacer for linker design.
- Supplied as a high-purity reagent suitable for research applications.
- Compatible with standard coupling and purification workflows.
![Medchemexpress LLC N-(4-aminobutyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide | 151294-96-1 | MFCD28397129 | 97.0% | 314.45 g/mol | C14H26N4O2S | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000204024.png-250.jpg)
Medchemexpress LLC N-(4-aminobutyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide | 151294-96-1 | MFCD28397129 | 97.0% | 314.45 g/mol | C14H26N4O2S | 250 MG
Biotin-C4-amide-C5-NH2 is a biotinylated, cleavable antibody-drug conjugate (ADC) linker supplied as a solid for research use. It contains a primary amine spacer for conjugation and is used for affinity-based capture and ADC synthesis workflows.
- Biotinylated cleavable linker for ADC synthesis.
- Primary amine functional group for conjugation.
- High purity, suitable for research applications.
- Solid form with standard storage recommendations for small molecules.